Top seed Daniil Medvedev powered through a rough patch to beat James Duckworth 6-2, 6-4 on Thursday and reach the quarter-finals of the ATP Toronto Masters.
The Russian produced 20 winners and 15 unforced errors on the way into a quarter-final against Pole Hubert Hurkacz, who scored a 6-7 (7/9), 6-4, 6-4 win over Nikoloz Basilashvili.
The Pole defeated Medvedev at Wimbledon only weeks ago.
Third-seeded Stefanos Tsitsipas celebrated his 23rd birthday with a solid 6-3, 6-2 victory over Olympic Silver medallist Karen Khachanov that put him into his fourth Masters 1000 quarter-final of the season.
The Greek set up a last-eight meeting with in-form Norwegian Casper Ruud, who extended his summer win streak to 13 matches.
The sixth-seeded Scandinavian, who won three straight claycourt titles before starting his hardcourt campaign this week, dispatched Serb Dusan Lajovic 6-4, 6-3.
Elsewhere, a 20-ace performance was more than enough to see John Isner through to the last eight as the Atlanta tournament champion won an eighth consecutive match, defeating fourth seed Andrey Rublev 7-5, 7-6 (7/5).
He next faces France’s Gael Monfils, who extended his career revival with a 6-1, 7-6 (7-2) defeat of American Frances Tiafoe.
American Reilly Opelka, who has eliminated Nick Kyrgios and Grigor Dimitrov this week, added Lloyd Harris to his victim’s list with a 4-6, 7-6 (8/6), 7-6 (7/4) comeback effort.
Spanish 10th seed Roberto Bautista Agut defeated Argentine eighth seed Diego Schwartzman 6-3, 3-6, 7-5 and next plays Opelka, whom he beat in the first round at Doha this season.