Top-ranked Iga Swiatek and U.S. Open champion Coco Gauff have been knocked out of the Miami Open.

Swiatek lost to Ekaterina Alexandrova 6-4, 6-2 on Monday night, hours after the third-seeded Gauff fell in three sets to No. 23 Caroline Garcia 6-3, 1-6, 6-2. In the men’s draw, top-seeded Carlos Alcaraz advanced to the round of 16 with a 6-4, 6-2 win over Gael Monfils.

Garcia defeated her second straight Grand Slam champion to reach Miami’s quarterfinals. She ousted four-time Grand Slam winner Naomi Osaka 7-6 (4), 7-5 on Sunday.

Garcia said it had been a while since she had a victory over a top-10 opponent like Gauff.

“You keep working and trying to stay positive about what’s coming, that it’s going to pay off,” she said. “Sometimes, it’s very hard. But I’m lucky enough to have very good people behind me to help me and stay positive when I’m struggling.”

“It means a lot to have this little reward and keep going in the tournament,” she said.

Also moving into the quarterfinals was No. 4 seed Elena Rybakina, who defeated 17th-seeded American Madison Keys 6-3, 7-5.

Rybakina will next face No. 8 seed Maria Sakkari, who advanced to her second Miami Open quarterfinal when Anna Kalinskaya, seeded 22nd, withdrew with a right thigh injury.

Victoria Azarenka, who’s won the Australian Open twice, made the quarterfinals with a 7-5, 6-1 victory over Katie Boulter.

Yulia Putintseva also advanced, defeating No. 27 seed Anhalina Kalinina straight sets, 6-4, 7-6 (5), and No. 5 seed Jessica Pegula beat Emma Navarro 7-6 (1), 6-3.

Alcaraz will next face Lorenzo Musetti, who beat Ben Shelton 6-4, 7-6 (5).

Alexander Zverev, the fourth seed, defeated Christopher Eubanks 7-6 (4), 6-3, and No.