US duo James Rothman and Randy Schekman and German-born Thomas Suedhof won the Nobel Medicine Prize on Monday for their groundbreaking work on how the cell organises its transport system, the jury said.
The trio, who all work at US universities, were honoured for “their discoveries of machinery regulating vesicle traffic, a major transport system in our cells,” it said.
Their discoveries have had a major impact on understanding how cargo is delivered within and outside the cell and have implications for work on several diseases including neurological and immunological disorders, as well as diabetes, the Nobel committee said. Each cell is a factory that produces and exports molecules.