The major Sensex gainers in Friday's trade were: Mahindra and Mahndra, up 4.53 percent at Rs.1,308.50; Maruti Suzuki, up 2.75 points at Rs.3,960; HDFC, up 2.29 percent at Rs.1,237.45; ONGC, up 2.02 percent at Rs.318.95; and Reliance Industries, up 1.78 percent at Rs.996.50.