Serbia lost to Chile in the first of their 2018 World Cup warm-up matches, conceding a late goal to Guillermo Maripan.
The centre-back headed in from close range two minutes from time to earn a deserved win for Reinaldo Rueda's side on Monday.
Former Manchester United and Wigan striker Angelo Henriquez missed an open goal from three yards out.
At the other end Newcastle United's Aleksandar Mitrovic was denied a penalty after Erick Pulgar's challenge.
The South American squad, which failed to qualify for the World Cup, dominated the first half on the efforts of Junior Fernandes and Angelo Sagal. It had rested stars Alexis Sanchez and Arturo Vidal for the friendly, opting for a younger side.
Serbia chose to leave Manchester United midfielder Nemanja Matic and lazio's Sergej Milinkovic-Savic on the bench, instead starting liverpool's Marko Grujic.
looking sluggish and sloppy, the Serbs created only one serious chance before the break, a strike by Aleksandar Kolarov in the 40th minute that tested Chile goalkeeper Gabriel Arias.
Serbia continue their tournament preparation with a friendly against Bolivia on Saturday before their opening Group E match against Costa Rica on June 17.
Five-time champions Brazil, Costa Rica and Switzerland are the other teams in Group E.
Morocco beat Slovakia
Geneva: Morocco impressed again in their World Cup preparation, beating Slovakia 2-1 in a warmup game on Monday.
After trailing to Slovakia's only shot on target, Morocco got goals midway through the second half from Ayoud Al Kaabi and Younes Belhanda.
Al Kaabi stooped in the goalmouth to guide a 63rd-minute header into the net after a corner was deflected to the far post. The corner was earned from goalkeeper Michael Sulla's excellent save to push away a header by little midfielder Mbark Boussoufa.
The winning goal in the 74th was a low bouncing shot struck by Younes Belhanda from the edge of the penalty area.
Slovakia led in the 57th when midfielder Jan Gregus scored with a low shot.
Morocco returned to Stade de Geneve from their Swiss Alps training camp four days after drawing with Ukraine 0-0 and showcasing their neat passing style.