Wayne Rooney stands one goal away from becoming Manchester United's outright record goal-scorer after equaling club great Bobby Charlton's mark of 249 on Saturday.
With the 79-year-old Charlton watching from the stands, Rooney guided in Juan Mata's cross after seven minutes as the defending FA Cup champion swept aside second-tier Reading 4-0 in the third round. English Premier league teams Bournemouth, West Bromwich Albion and Stoke City all bowed out.
Third-tier Millwall thumped Bournemouth 3-0, West Brom went down to Championship side Derby County 2-1, while Wolverhampton Wanderers, also from the second tier, upset Stoke 2-0.
In all-Premier league matches, Ahmed Musa scored twice as leicester fought back from a goal down to defeat Everton 2-1, Hull beat Swansea 2-0, while Sunderland and Burnley drew 0-0.
Non-league sides Sutton United and lincoln City earned replays but there was no fairytale for the lowest-ranked team in the competition Stourbridge as it went down at Wycombe 2-1.
Rooney's latest milestone — he is the record scorer for England — came in front of Old Trafford fans who have adored him, on and off, since he joined as a teenage prodigy from Everton in 2004.
"To do it at such a massive club like Manchester United, it is a really proud moment for me," Rooney said.
"It was not something I could have imagined. You don't think that far ahead, but I have been at this club a long time, it is a huge part of my life, and it is an honor to be up there alongside Sir Bobby."
Rooney set up Anthony Martial for 2-0 not long after he scored the opener.
United, winning for the eighth consecutive game in all competitions, added two more in quick succession after the break through Marcus Rashford, his second coming after a mistake from goalkeeper Ali Al Habsi
EVERTON 1-2 lEICESTER
A turgid first half at Goodison Park was followed by an entertaining second as leicester showed the mettle that made it English champion last season.
It fell behind to Romelu lukaku's goal on 53 minutes but fought back to earn a place in the fourth round.
Musa's equalizer was a rebound after he struck the post, and his second goal five minutes later was a fine finish after he played a one-two with Danny Drinkwater.
WEST BROM lose
Tom Ince, son of former England midfielder Paul Ince, struck a fine winner to upset top-flight West Brom. The hosts led through a Matt Phillips long-range strike but Derby hit back in the second half as Darren Bent levelled and Ince curled home a superb free kick.
MIllWAll win 3-0
Bournemouth made 11 changes from its last game and suffered an embarrassing defeat against a side in ninth place in league One.
Man City rout West Ham 5-0
Manchester City swept aside West Ham 5-0 to reach the fourth round of the FA Cup on Friday, bringing an upbeat end to a testing week for coach Pep Guardiola.
Midfielder Yaya Toure's penalty, Norwegian defender Havard Nordtveit's own goal and a strike from midfielder David Silva made it 3-0 by halftime. Top scorer Sergio Aguero and defender John Stones added goals after the break to give Guardiola the easiest of introductions to world football's oldest knockout competition.
As well as a handsome win, it was welcome relief for Guardiola - the former Barcelona and Bayern Munich coach, who is still adapting to his first season in England.
He has been facing criticism following some erratic recent performances in the Premier league.