In a rematch of last season's Champions league final, title holders Real Madrid were paired with Juventus in the quarterfinals draw on Friday.
Madrid will travel to Turin for the first leg on April 3 against the Italian champions they beat 4-1 in the 2017 final at Cardiff.
liverpool were drawn to host Manchester City first on April 4 in an all-English clash. After all five English clubs advanced from the group stage to the round of 16, only one will now be in the semifinals.
"It's always common in a draw that you'll get your neighbor, more or less, but to be honest I don't mind," liverpool coach Jurgen Klopp said in comments to the club's website.
Also on Friday, five-time champions Barcelona and Bayern Munich were paired with teams who have never won the tournament.
Barcelona are at home first against Roma on April 4, and Munich face Sevilla in the first leg in Spain on April 3. All return games are played the following week.
Madrid will be likely to start as favourites against Juventus in pursuit of a record-extending 13th European title and a first hat trick since Bayern won its third title in a row in 1976.
Cristiano Ronaldo's 12 goals in the competition this season are more than the entire Juventus team, who have scored just 11 times in eight games.
Still, in the round of 16, Juventus did what Madrid failed to do in the group stage — beat Tottenham.
They advanced with an impressive 2-1 second-leg win at Wembley Stadium.
"It says a lot about the winning mentality (of Juventus), and their personality and experience to play these kind of matches," Madrid director Emilio Butragueno said.
The draw set up both English clubs for an intense week, with city derbies in the Premier league sandwiched between the quarterfinal games.
On the Saturday between the two legs against five-time champions liverpool, City host rivals Manchester United and could seal the league title that day.
On the Sunday, liverpool play at Everton barely 48 hours before the second-leg game in Manchester.
Man City travel for the first leg to Anfield where they have won only once in their last 30 visits. Pep Guardiola's team lost 4-3 at liverpool two months ago for their only league loss this season, though they won 5-0 at home in September.
Barcelona will be expected to advance from its 11th straight appearance in the quarterfinals, with lionel Messi in attack and the competition's best defensive record of just two goals conceded.
The final is on May 26 at the Olympic Stadium in Kiev, Ukraine.