Defending champion Roger defeats Mannarino in straight sets, Nadal also advances
Roger Federer needed just 16 minutes to win the opening set in a 6-0, 7-5, 6-4 defeat of France's Adrian Mannarino to reach his 16th Wimbledon quarter-final on Monday.
Eight-time champion Federer will be playing in his 53rd Grand Slam last-eight when he tackles Kevin Anderson, the eighth-seeded South African.
Top seed Federer, 36, has now won 32 consecutive sets at Wimbledon, just two behind his record set from the third round in 2005 to his title triumph in 2006.
"It was crucial for him to stay in the match at the beginning of the second set and then it got tougher," said Federer after his sixth win in six meetings against French left-hander Mannarino.
"You always tend to play better against better players and I am happy to be back in the second week of Wimbledon." Federer boasts a 4-0 career record against 2017 US Open runner-up Anderson and 9-4 over Monfils.
Monfils and Anderson have yet to get to the quarter-finals at Wimbledon, although the French shotmaker may just be the slight favourite as he has a 5-0 winning record over the big South African.
Also, Rafael Nadal reached the Wimbledon quarterfinals for the first time since 2011.
The top-ranked Spaniard beat Jiri Vesely 6-3, 6-3, 6-4 on Centre Court to return to the last eight for the first time since he was runner-up to Novak Djokovic in 2011.
Nadal, a two-time champion at the All England Club, has yet to drop a set in this tournament. He was down a break in the third set but broke right back for 3-3 and then converted his third match point when Vesely missed a backhand.
18 in a row
Serena Williams underlined her status as the Wimbledon title favourite with a 62-minute demolition of Russian qualifier Evgeniya Rodina, while Karolina Pliskova became the last top 10 seed to crash out on Monday.
Williams raced into her 13th Wimbledon quarter-final as the seven-time champion thrashed Rodina 6-2, 6-2 in a Centre Court masterclass.
Williams, who won the Wimbledon title on her last two visits in 2015 and 2016, is now on an 18-match winning streak at the All England Club.
Having missed Wimbledon last year while she prepared to have her first child in September, Serena is in pole position to win her first Grand Slam crown since becoming a mother.
On Tuesday, the 36-year-old faces Italian world number 52 Camila Giorgi, who beat Russia's Ekaterina Makarova 6-3, 6-4 to reach her first Grand Slam quarter-final. Asked if it was a flawless display, Serena admitted she is never satisfied.
"I'm a perfectionist. I always find something wrong," she said.
Serena's 90th Wimbledon win of her career is the most among active female players. Williams had made a tentative return to action following complications during daughter Olympia's birth, struggling in her few appearances before pulling out midway through the recent French Open with a pectoral injury.
But the 23-time major winner's blistering form and a series of shock results have paved the way for another Williams coronation at Wimbledon.
Garbine Muguruza, Maria Sharapova, Simona Halep, Petra Kvitova, Venus Williams, Caroline Wozniacki and Sloane Stephens have all been eliminated already. Kiki Bertens took care of the last of the top 10 with a 6-3, 7-6 (7/1) victory over Czech seventh seed Pliskova.
It is the first time in Wimbledon history not one of the top 10 women's seeds have reached the quarter-finals.
Bertens, who was contemplating retirement last year after losing her enthusiasm for the sport, is the first Dutch woman to reach the Wimbledon quarter-finals since Michaella Krajicek in 2007.
The 26-year-old faces German 13th seed Julia Goerges, who beat Croatian world number 55 Donna Vekic 6-3, 6-2 to seal her first Grand Slam quarter-final berth at the 42nd attempt.
Elsewhere in fourth round action, Dominika Cibulkova launched a scathing attack on Wimbledon's officials after a line call controversy marred her 6-4, 6-1 win against Taiwan's Hsieh Su-Wei.
latvian 12th seed Ostapenko enjoyed a 7-6 (7/4), 6-0 win against Belarusian world number 50 Aliaksandra Sasnovich.
Former Wimbledon finalist Angelique Kerber stepped up her bid to return to the title match with a 6-3, 7-6 (7/5) win against Switzerland's Belinda Bencic. Kerber, who won the Australian and US Open titles in 2016, is seeded 11th -- making her the highest ranked woman left in the draw.
Beaten by Serena in the 2016 final, Kerber takes on Russian 14th seed Daria Kasatkina, a 6-7 (6/8), 6-3, 6-2 winner against Belgian world number 47 Alison Van Uytvanck.