The IIIM, Jammu based laboratory of the CSIR has joined hands with Reliance Industries (RIL) to develop and scale-up a new Reverse Transcriptase-Loop Mediated Isothermal Amplification (RT-LAMP) based Covid-19 diagnostic kit.
A memorandum of understanding has been signed between CSIR-IIIM, Jammu and RIL on Tuesday.
Covid-19 RT-LAMP test is a nucleic acid based test carried out from nasal/throat swab sample from patients.
“The test recipe has been developed and successfully demonstrated using synthetic templates. It is rapid (45-60 min), cost effective and accurate test.
It has been tested with a small number of patients samples and validating the kit on more number of patient samples is planned and will be done together with RIL,” said a statement here from the CSIR, a research agency under the Union Science and Technology Ministry.
The advantage of this test is that the RT-LAMP based Covid-19 kit components are easily available and these can be completely manufactured in India, it added.
While the, the current Covid-19 testing is done by real-time PCR, their components are mostly imported. Further these tests are expensive; require highly trained manpower, costly instruments and a relatively high-end lab and cannot be deployed at remote locations in quarantine centers, airports and railway stations, etc, said the CSIR.
On the other hand, the RT-LAMP test can be done in a single tube with minimal expertise in a very basic lab setup like mobile units / kiosks for testing at airports, railway stations, bus stands and other public places. The end detection of the test is a simple colored reaction, which is easily visible in UV light, and now is being modified such that it can be detected in regular light, the statement added.
After testing the accuracy of the kit, on a much larger number of patients, CSIR-IIIM and RIL will jointly approach the ICMR for approval.
With the formal launch of the RT-LAMP based diagnostic test, the Covid-19 testing will not only be more rapid, cheap, easy and accessible but also would go a long way quickly isolating the infected individuals and mitigating the spread of virus, said the statement.
Dr. Ram Vishwakarma, Director and Dr. Sumit Gandhi, Principal Scientist from CSIR-IIIM and Dr. Santanu Dasgupta, Senior Vice President, R&D and Dr. Manish Shukla, General Manager R&D from RIL side are monitoring this project, as per the statement.