The US-based study published in the Journal of Clinical Psychiatry found that 69 per cent of people taking anti-depressants did not meet the criteria for major depressive disorder, also known as clinical depression. "Many individuals prescribed anti-depressants may not have met the criteria for mental disorders," the researchers were quoted as saying. "Our data indicates that anti-depressants are commonly used in the absence of clear evidence-based indications," the researchers noted.