As many as three youths were killed and two others seriously injured in a collision between a car and a truck on National Highway-149 at Naikanali village under the Samal police station in the district on Saturday.
While the identities of the deceased were yet to be ascertained, the injured were admitted to a hospital in Talcher, sources said.
The incident took place in the morning when the five youths were returning to Rourkela after attending a wedding in Jankia area of Khordha district.
The car by which they were travelling collided head on with the speeding truck at Naikanali village. The truck driver fled from the spot with his vehicle after the accident.
On getting information, police reached the spot and began an investigation into the incident.