US Secretary of State Antony Blinken urged Israel and the Palestinians on Monday to exercise restraint and ease tensions amid a spike in violence that has put the region on edge.

Speaking in Cairo, just hours ahead of a two-day visit to Jerusalem and the West Bank, Blinken said it is imperative for both sides to work to de-escalate tensions that have soared since last week in what he called “a new and horrifying surge in violence” and prompted severe responses from each.

“We will be encouraging the parties to take steps to calm things down,” Blinken told reporters at a joint news conference with Egyptian Foreign Minister Sameh Shoukry. “There is no question that this is a very difficult moment."

He repeated US condemnations of militant attacks against Israelis and noted that “we deplore overall the loss of innocent civilian life."

The latest spate of violence erupted last week with an Israeli military raid on a militant stronghold in the West Bank city of Jenin last week that killed 10 people, most of them militants, and a Palestinian shooting attack in an east Jerusalem Jewish settlement that killed seven Israelis.

And, on Monday, shortly before Blinken's arrival, the Palestinian Health Ministry said Israeli forces killed a Palestinian man in the flashpoint city of Hebron, bringing the toll of Palestinians killed in January to 35.

The violence comes after months of Israeli arrest raids in the West Bank, which were launched after a wave of Palestinians attacks against Israelis in the spring of 2022 that killed 19 people.

But it has spiked this month during the first weeks of Israeli Prime Minister Benjamin Netanyahu's new far-right government, which has promised to take a tough stance against the Palestinians and ramp up settlement construction.